АЛЬПИНИЯ ЛЕКАРСТВЕННАЯ (ALPINIA OFFICINARUM).
ПУБЛИКАЦИЯ 3: БИОЛОГИЧЕСКОЕ ДЕЙСТВИЕ, ПРИМЕНЕНИЕ В ТРАДИЦИОННОЙ МЕДИЦИНЕ И СОВРЕМЕННОЙ МИРОВОЙ МЕДИКО-ФАРМАЦЕВТИЧЕСКОЙ ПРАКТИКЕ
Ключевые слова:
традиционная медицина, альпиния лекарственная, Alpinia officinarum, флавоноиды, диарилгептаноиды, фенилпропаноиды, терпены, аддукты ДАГ-терпеновой природы, противовирусное действие, противоопухолевое действие, противомикробное действие, антиоксидантное действие, противовоспалительное действие, нейропротективное действиеАннотация
Проведенное информационно-аналитическое исследование позволило установить доказанную эффективность и безопасность экстрактов корневищ Alpinia officinarum. Выявлены работы, описывающие механизмы действия БАВ а. лекарственной, а также процессы, обусловливающие противоопухолевый и некоторые другие установленные биологические эффекты. Показано, что наряду с высокой эффективностью некоторые изученные БАВ проявляют селективность, что позволяет считать их перспективными источниками для создания натуральных ЛС, БАД к пище и СПП. Токсические эффекты не выявлены.
Основными группами БАВ, ответственными за широкий спектр фармакотерапевтического действия корневищ малого галангала, можно считать фенолы (флавоноиды, диарилгептаноиды (ДАГ), фенилпропаноиды), терпены, фитостерины и аддукты ДАГ-терпеновой природы. Фенольная фракция, полученная с помощью различных растворителей, как и отдельные БАВ, включая аддукты ДАГ и терпенов, проявляют выраженное антипролиферативное, антиоксидантное, противовоспалительное, противовирусное, нейропротективное, антиостеопоротическое, противоязвенное, антигиперлипидемическое действие. Терпены (в том числе дитерпены), в основном, ответственны за противомикробное, противовоспалительное, антипролиферативное, противовирусное действие.
Полученные результаты свидетельствуют о высоком нутрицевтическом потенциале и хороших перспективах применения альпинии лекарственной в мировой медикофармацевтической практике в качестве источника ЛС, БАД к пище и СПП.
Библиографические ссылки
Альпиния оффициналис – Alpinia officinalis, альпиния лекарственная // Справочник по гомеопатии [Электронный ресурс]. – Доступ: http://med.niv.ru/doc/dictionary/homeopathy/fc/slovar-192-2.htm (по состоянию на 29.04.2020)
Амасиаци, А. Ненужное для неучей / А. Амасиаци. – М.: Наука, 1990. – Т.13. – 880 с.
Барнаулов, О.Д. Лекарственные свойства пряностей. 2-е изд. перераб. и доп. / О.Д. Барнаулов. – Саб.: Информ-Навигатор, 2015. – 288 с.
Лекарственные свойства пряностей / О.Д. Барнаулов, М.Л. Поспелова, С.О. Барнаулова, А.С. Бенхаммади. – СПб.: Изд-во Фонда русской поэзии, 2001. – 240 с.
Белодубровская, Г.А. Номенклатура гомеопатических средств: Методич. пособие / Г.А. Белодубровская, Е.В. Зданевич; Под общ. ред. проф. К.Ф. Блиновой. – СПб: СПГХФА, 1996. – 32 с.
Белодубровская, Г.А. Номенклатура лекарственных растений, используемых в гомеопатии: Методич. Пособие / Г.А. Белодубровская, Е.В. Жохова. – СПб.: СПбХФА, 1998. – 59 с.
Белоусов, П.В. Корневище альпинии лекарственной – Rhizoma Alpiniae Officinari / П.В. Белоусов // Иллюстрированный атлас лекарств китайской медицины: лекарства, прогревающие внутренние органы [Электронный ресурс]. – Доступ: http://belousov.kz/atlas/124.html (по состоянию на 28.04.2020)
Белоусов, П. В. Основы китайской фитотерапии / П.В. Белоусов, А.В. Чемерис. – Алматы, 2010. – 198 с.
Значение химических свойств оксида азота для лечения онкологических заболеваний / Д.А. Винк, Й. Водовоз, Дж.А. Кук [и др.] // Биохимия. – 1998. – Вып.7. – С.948–957.
Виноградов, Н.А. Многоликая окись азота / Н.А. Виноградов // Российский журнал гастроэнторологии, гепатологии, колопроктологии. – 1997. – №2. – С.6–11.
Галанга // Справочник по гомеопатии [Электронный ресурс]. – Доступ: https://homeopathy.academic.ru/1222/Галанга_-_Galanga%2C_Альпиния_лекарственная (по состоянию на 15.02.2020)
Галанга // Энциклопедический словарь Брокгауза и Ефрона: в 86 т. (82 т., 4 доп.). – СПб., 1890–1907. – Т. 7А (14): Выговский – Гальбан. – 1892. – 952 с. (С. 887).
Галанга // Энциклопедия пряностей [Электронный ресурс]. – Доступ: http://www.trapeza.tv/enc/enc_list.php?enc=28 (по состоянию на 10.02.2020)
Государственный реестр лекарственных средств (VII ежегодное периодическое издание). – М.: Техническая книга, 2002. – 1301 с.
Грищук, Н.А. Мир пряностей и специй / Н.А. Грищук. – Луцк: Друкмаркет, 2010. – 192 с.
Губанов, И.А. Лекарственные растения и грибы, используемые в гомеопатии. Краткий справочник / И.А. Губанов, А.В. Патудин, А.М. Рабинович. – М.: Гомеопатический центр, 1995. – 112 с.
Дудченко, Л.Г. Пряно-ароматические и пряно-вкусовые растения: Справочник / отв. ред. К. М. Сытник (АН Украинской ССР) / Л.Г. Дудченко, А.С. Козьяков, В.В. Кривенко. – К.: Наукова думка, 1989. – 304 с. – (Галгант. – С.28–49).
Лекарственные растения, используемые в гомеопатии, и отечественная сырьевая база для производства гомеопатических лекарственных средств / Т.Л. Киселева, А.А. Карпеев, И.А. Самылина, А.В. Нефедова // В кн. Гомеопатическая фармация: введение и руководство / сост. Киселева Т.Л., Карпеев А.А. – М.: Изд-во ФНКЭЦ ТМДЛ Росздрава, 2005. – С.228–438.
Киселева, Т.Л. Альпиния лекарственная (Alpinia officinarum) в традиционной медицине и современной медико-фармацевтической практике. Публикация 1: ботаническая характеристика, синонимика, особенности заготовки сырья, пищевое применение / Т.Л. Киселева, Н.В. Колман // Традиционная медицина. – 2020. – № 2 (61). – С.20–35.
Киселева, Т.Л. Альпиния лекарственная (Alpinia officinarum) в традиционной медицине и современной медико-фармацевтической практике. Публикация 2: химический состав и биологически активные вещества, обусловливающие фармакотерапевтическое действие / Т.Л. Киселева, Н.В. Колман // Традиционная медицина. – 2020.- № 3 (62). – С.15–32.
Киселева, Т.Л. Номенклатура производящих растений и сырья для производства гомеопатических лекарственных средств в России. Справочное пособие / Т.Л. Киселева, Е.В. Цветаева. – М.: Изд-во НПЦ традиционной медицины и гомеопатии МЗ РФ, 2002. – 124 с.
Лад, В. Травы и специи / В. Лад, Д. Фроули; Пер. с англ. - М.: Саттва, 2000. – 304 с.
Защитные и повреждающие эффекты периодической гипоксии: роль оксида азота / Е.Б. Манухина, Х.Ф. Дауни, Р.Т. Маллет, И.Ю. Малышев // Вестник Рос. АМН. – 2007. – №2. – С.25–33.
МЗ и МП РФ: Об использовании метода гомеопатии в практическом здравоохранении / Приказ от 29.11.95 г. № 335.
Миконенко, А.Б. Фитотерапия в традиционной китайской медицине / А.Б. Миконенко. – М.: Профит Стайл, 2010. – 304 с.
Одо из Мена. О свойствах трав (перевод с латинского и комментарии Ю.Ф.Шульца) / Одо из Мена; Под общ. ред. В.Н. Терновского. – М.: Медицина, 1976. – 272 с.
О’ Коннел, Дж. Энциклопедия специй. От аниса до шафрана / Дж. О’ Коннел; Пер. с англ. Е.Н.Кручины. – М.: Эксмо, 2018. – 352 с.
Похлебкин, В.В. Калган / В.В. Похлебкин // В кн.: Большая энциклопедия кулинарного искусства. – М.: Издательство: Центрполиграф, 2009. – 975 с.
Похлебкин, В.В. Все о пряностях / В.В. Похлебкин. – М.: ЗАО Центрполиграф, 2010. – 207 с.
Похлебкин, В.В. Пряности / В.В. Похлебкин // В кн.: Кулинарный словарь. – М.: Изд-во «Э», 2015. – 456 с.
Похлебкин, В.В. Кулинарный словарь / В.В. Похлебкин. – М.: Изд-во «Э», 2015. – 456 с.
Похлебкин, В.В. Большая кулинарная книга / В.В. Похлебкин. – М.: Изд-во «Э», 2017. – 992 с.
Сайфутдинов, Р.Г. Роль оксида азота при заболеваниях внутренних органов (обзор) / Р.Г. Сайфутдинов // Вестник современной клинической медицины. –2009. – №3. – С. 48–53.
Сы, Х. Основы китайской медицины / Х. Сы, Л. Лузина, Ц. Сы. – М.: Медицина, 2009. –660 с.
Упур, Х. Секреты китайской медицины / Х. Упур, В.Г. Начатой. – СПб: Изд-во им. А.С. Суворина, 1992. – 204 с.
Хэлперн, М. Уроки на пути аюрведы / М. Хэлперн; Пер. с англ. – М.: Саттва, 2017. – 256 с.
Чойжинимаева, С.Г. Тибетские рецепты здоровья и долголетия / С.Г. Чойжинимаева. – М.: Издательство Эксмо, 2017. – 384 с.
Шедо, А. Пряности / А. Шедо, И. Крейча. – Братислава, 1985. – 252 с.
Шретер, А.И. Природное сырье китайской медицины. Т. 1 / А.И. Шретер, Б.Г. Валентинов, Э.М. Наумова. – М.: «Теревинф», 2004. – 506 с.
Шубин, В.Е. Исследование методом ЭПР образования окиси азота при восстановлении нитрофуранов и нитроимидазолов. I. Растворы гемоглобина / В.Е. Шубин, З.В. Куроптева // Studia biophysica. – 1983. – Vol. 97. – №2. – P.157–164.
Stored-product insects in botanical warehouses / A.Y. Abdelghany, S.S. Awadalla, N.F. Abdel-Baky [et al.] // J. Stored Prod. Res. – 2010; 46: 93–97.
Cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction and cerebrovascular accident / N.S. Abraham, H.B. El-Serag, C. Hartman [et al.] // Aliment. Pharmacol. Ther. – 2007; 25: 913–924.
A review on the ethnomedicinal uses, phytochemistry and pharmacology of Alpinia officinarum Hance / I.B. Abubakar, I. Malami, Y. Yahaya, S.M. Sule // J. Ethnopharmacol. – 2018; 224: 45–62.
Analysis of Alpina officinarum Hance, chemically and biologically / F.A. Alasmary, E.A. Assirey, R.M. El-Meligy [et al.] // Saudi Pharm J. – 2019 Dec; 27(8): 1107–1112. Published online 2019 Sep 25.
Structural features, kinetics and SAR study of radical scavenging and antioxidant activities of phenolic and anilinic compounds / H.M. Ali, A. Abo-Shady, H.A. Sharaf Eldeen [et al.] // Chem. Cent. J. – 2013; 7: 53.
Blepharocalyxins C–E: three novel antiproliferative diarylheptanoids from the seeds of Alpinia blepharocalyx / M.S. Ali, Y. Tezuka, A.H. Banskota, S. Kadota // Tetrahedron letters. – 2000; 41(31): 5903–5907.
Alpinia officinarum // Wikipedia [Электронный ресурс на англ. яз.]. – Доступ: https://en.wikipedia.org/wiki/Alpinia_officinarum (по состоянию на 25.01.2020).
Altman, R.D. Effects of a ginger extract on knee pain in patients with osteoarthritis / R.D. Altman, K.C. Marcussen // Arthritis Rheuma. – 2001; 44: 2531–2538.
Diarylheptanoids from the rhizomes of Alpinia officinarum and their anticancer activity / N. An, Z.M. Zou, Z. Tian [et al.] // Fitoterapia. – 2008; 79: 27–31.
Anand David, A.V. Overviews of Biological importance of Quercetin: A Bioactive Flavonoid / A.V. Anand David, R. Arulmoli, S. Parasuraman // Pharmacogn. Rev. – 2016; 10: 84–89.
Aruoma, O.I. Assessment of potential prooxidant and antioxidant actions / O.I. Aruoma // J. Amer. Oil Chem. Society. – 1996; 73(12): 1617–1625.
Novel Compounds with new Anti-Ulcergenic Activity from Convolvulus pilosellifolius using Bio-Guided Fractionation / S.A. Awaad, A. Al-Refaie, R.M. El-Meligy [et al.] // Phytother. Res. 2016;30:2060–2064.
Quantitative and qualitative analysis for Standardization of Euphorbia cuneata Vahl / S.A. Awaad, M.R. Alothman, Y.M. Zain [et al.] // Saudi Pharmaceut. J. – 2018; 25: 1175–1178.
Awang, D. Ginger / D. Awang // Can Pharm J. 1992;125:309–311.
Basri, A.M. A review on the pharmacological activities and phytochemicals of Alpinia officinarum (Galangal) extracts derived from bioassay-guided fractionation and isolation / A.M. Basri, H. Taha, N. Ahmad // Pharmacogn. Rev. – 2017; 11(21): 43–56.
Baumann, J. Prostaglandin synthetase inhibiting O2-radical scavenging properties of some flavonoids and related phenolic compounds / J. Baumann, G. Wurn,
F.V. Bruchlausen // Naunyn-Schmiedebergs Arch. Pharmacol. – 1979; 308: 27–32.
Antioxidant and structure-activity relationships (SARs) of some phenolic and anilines compounds / E. Bendary, R.R. Francis, H.M. Ali [et al.] // Ann Agric Sci. – 2013; 58: 173–181.
, The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines, American Botanical Council, Austin, TX and Integrative Medicine Communications / M. Blumenthal [et al.]; Eds. –Boston, MA, 1998.
Bown, D. The Royal Horticultural Society Encyclopedia of Herbs and Their Uses / D. Bown. – London: Dorling Kindersley Limited, 1995. – 424 p.
Brewer, M.S. Natural antioxidants: Sources, compounds, mechanisms of action, and potential applications / M.S. Brewer // Compr. Rev. Food Sci. Food. Saf. – 2011; 10: 221–247.
Bu, X. Chemical study of Alpinia offcinarum / X. Bu, G. Xiao, L. Gu // Zhong Yao Cai. – 2000; 23: 84–87.
Byler, K.G. In-silico screening for anti-Zika virus phytochemicals / K.G. Byler, I.V. Ogungbe, W.N. // J. Mol. Graph. Model. – 2016; 69: 78–91.
Galangin inhibits cell invasion by suppressing the epithelial-mesenchymal transition and inducing apoptosis in renal cell carcinoma / J. Cao, H. Wang, F. Chen [et al.] // Mol. Med. Rep. – 2016; 13: 4238–4244.
Carocho, M. The role of phenolic compounds in the fight against cancer – a review / M. Carocho, I.C.F.R. Ferreira // Anti-Cancer Agents Med. Chem. – 2013; 13: 1236–1258.
Chang, C.L. Phytochemical Composition, Antioxidant Activity, and Neuroprotective Effect of Terminalia chebula Retzius Extracts / C.L. Chang, C.S. Lin // Evid. Based Complement. Alternat. Med. – 2012; 2012:125247.
Chang, C.L. Phytochemical characteristics, free radical scavenging activities, and neuroprotection of five medicinal plant extracts / C.L. Chang, C.S. Lin, G.H. Lai // Evid. Based Complement. Alternat. Med. –2012: 984295. – Published online 2011 Aug. 10.; 2012 Article ID 984295, 8 p.
Clemett, D. Raloxifene: a review of its use in postmenopausal osteoporosis. Drugs / D. Clemett, C.M. Spencer. –2006; 60: 379–411.
CN104138368A. Preparation method and cancer treatment effect of rhizome Alpiniae officinarum aboveground part AO-95; 12 November. – 2014.
Protective effects of methyl gallate on H2O2-induced apoptosis in PC12 cells / J.A. Crispo, M. Pich?, D.R. Ansell [et al.] // Biochemical and Biophysical Research Communications. – 2010; 393(4): 773–778.
Crouzet, J. Glycosidically bound volatiles in plants / J. Crouzet, D. Chassagne // In: Ikan R., editor. Naturally Occurring Glycosides. – Chichester, England: John Wiley and Sons Ltd, 1999. – Р.225–274.
Salvianolic acid B prevents bone loss in prednisone-treated rats through stimulation of osteogenesis and bone marrow angiogenesis / L. Cui, T. Li, Y. Liu [et al.] – PLoS One. 2012;7:e34647.
Culpeper Nicolas. Complete Herbal (1653) / Nicolas Culpeper. – Wordsworth, 1995. – P.313–314.
Aggregation of Staphylococcus aureus following treatment with the antibacterial flavonol galangin / T.P.T. Cushnie, V.E.S. Hamilton, D.G. Chapman [et al.] // J. Appl. Microbiol. – 2007; 103: 1562–1567.
A prospective study of postmenopausal hormone use and ovarian cancer risk / K.N. Danforth, S.S. Tworoger, J.L. Hecht [et al.] // Br J Cancer. 2007;96:151–156.
Galangal, the multipotent super spices: A comprehensive review / G. Das, J.K. Patra, S. Gon?alves [et al.] // Trends in Food Science and Technology. – 2020; 101: 50–62. (2020).
Das, K. Techniques for evaluation of medicinal plant products as antimicrobial agent: Current methods and future trends / K. Das, R.K. Tiwari, D.K. Shrivastava // J. Med. Plants Res. – 2010; 4: 104–111.
Deng, Y.F. Determination of the content of galangin in Alpinia officinarum Hance harvested in different months by RP-HPLC / Y.F. Deng, L.N. Feng, H. Luo // Chin. Pharm. J. – 2010; 45: 1593–1596.
Di Rosa, M. Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine / M. Di Rosa, J.P. Giroud, D.A. Willoughby // J. Pathol. – 1971; 104: 15–29.
Ding, W. The main stratagems and technology for stored product pest control in ancient China / W. Ding, H. Liu, L.S. Li // J. Southwest Agric. Univ. - 2000; 22: 335–338.
Diterpenes labdane // Big Chemical Encyclopedia: chemical substances, components, reactions, process design [Электронный ресурс на англ. яз.]. – Доступ: https://chempedia.info/info/labdane_diterpenes/ (по состоянию на 13.03.2020)
Duke, J.A. Handbook of Medicinal Herbs / J.A. Duke. – Boca Raton-London-New York-Washington: CRC Press, 2002. – 896 p.
Duke, J.A. Medicinal Plants of China, 2 vols. / J.A. Duke, E.S. Ayensu. – Reference Publications, Algonac, MI, 1985.
CRC handbook of medicinal spices / J.A. Duke, M.J. Bogenschutz-Godwin, J. duCellier [et al.] – Boca Raton-London-New York-Washington, D.C.: CRC Press, 2003. – 333 p.
Resveratrol supplementation preserves long bone mass, microstructure, and strength in hindlimb-suspended old male rats / S.M. Durbin, J.R. Jackson, M.J. Ryan [et al.] // J Bone Min Metab. – 2014; 32: 38–47.
Prophylactic and curative anti-ulcerogenic activity and the possible mechanisms of action of some desert plants / R.M. El-Meligy, A.S. Awaad, G.A. Soliman [et al.] // Saudi Pharmaceut. J. – 2017; 25: 387–396.
The interaction of flavonoids with membranes: potential determinant of flavonoid antioxidant effects / A.G. Erlejman, S.V. Verstraeten, C.G. Fraga, P.I. Oteiza // Free Radic. Res. – 2004; 38: 1311–1320.
Study on anti-obese and hypolipidemic effects of total flavonoids from Alpinia officinarum Hance in rats with nutritive obesity combined with hyperlipidemia / Y.J. Fang, D.Z. Xia, S.W. Wang, S.S. Ji // China Journal of Traditional Chinese Medicine and Pharmacy. – 2015; 30(8), 2907–2910.
Chemopreventive mechanisms of galangin against hepatocellular carcinoma: A review / D.Y. Fang, Z.M. Xiong, J.M. Xu [et al.] // Biomed. Pharmacother. – 2019; 109: 2054–2061.
Icariin protects against glucocorticoid-induced osteoporosis in vitro and prevents glucocorticoid-induced osteocyte apoptosis in vivo / R. Feng, L. Feng, Z. Yuan [et al.] // Cell Biochem Biophys. 2013;67:189–197.
Effect of glucocorticoid-induced oxidative stress on the expression of Cbfa1 / Y.L. Feng, X.L. Tang // Chem Biol Interact. 2014;207:26–31.
Interrelation of oxidative stress and inflammation in neurodegenerative disease: role of TNF / R. Fischer, O. Maier // Oxid Med Cell Longev. – 2015. 2015 610813.
Flannery, M. Avicenna / M. Flannery // Britannica [Электронный ресурс на англ. языке]. – Доступ:
https: //www.britannica.com/biography/Avicenna (по состоянию на 01.08.2020)
PDR for Herbal Medicine, 1st ed. / T. Fleming [et al.] – Medical Economics Co., Montvale, NJ, 1998.
Gass, M. Preventing osteoporosis-related fractures: an overview / M. Gass, B. Dawson-Hughes // Am. J. Med. – 2006; 119:S3–S11.
Epicalyxin F and calyxin I: two novel antiproliferatire diarylheptanoids from the seeds of Alpinia blepharocalyx / M.B. Gewali, Y. Tezuka, A.H. Banskota [et al.] // Organic letters 1999; 1(11): 1733–1736.
In vitro antioxidant activity of Tectona grandis Linn / M. Ghaisas, V. Navghare, A. Takawale [et al.] // Pharmacol. Online. – 2008; 3: 296–305.
GHP (German Homoeopathic Pharmacopoeia); 5th еd. issued in 2001. - Deutscher Apotheker Verlag / Ad-Ex Translation Ltd, Medpharm Scientific Publishers, London: CRC Press, 2003. – 1772 р. – ISBN 3-88763-095-5
Ghil, S. Antiproliferative activity of Alpinia officinarum extract in the human breast cancer cell line MCF-7 / S. Ghil // Mol. Med. Rep. – 2013; 7: 1288–1292.
Ghosh, S. Alpinia: The gold mine of future therapeutics / S. Ghosh, L. Rangan // 3 Biotech. 2013;3:173.
Effects and possible mechanisms of Alpinia officinarum ethanol extract on indomethacin-induced gastric injury in rats / J. Gong, Zh. Zhang, X. Zhang [et al.] // Pharmaceutical Biology. – 2018; 56: 1, 294–301.
Effect of growth hormone therapy on nitric oxide formation in cystic ?brosis patients / C. Grasemann, F. Ratjen, D. Schnabel [et al.] // Eur. Respir J. – 2008. – Vol.31. – P.815–821.
Grieve, M. A Modern Herbal / M. Grieve. – New York: Hafner Press, 1931; Dover reprint, 2 vols, 1st reprinted 1971, Dover, New York
Gr?blacher, B. Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium Smegmatis / B. Gr?blacher, O. Kunert, F. Bucar // Bioorganic & Medicinal Chemistry 2012; 20(8): 2701–2706.
PDR for Herbal Medicines, 2nd ed. / J. Gruenwald [et al.]. – Medical Economics Co., Montvale, NJ, 2000.
Double directional adjusting estrogenic effect of naringin from Rhizoma drynariae (Gusuibu) / D. Guo, J. Wang, X. Wang [et al.] // J Ethnopharmacol. 2011;138:451–457.
Galangin, a flavonol derived from rhizoma Alpiniae officinarum inhibits acetylcholinesterase activity in vitro / A.J. Guo, H.Q. Xie, R.C. Choi [et al.] // Chem. Biol. Interact. – 2010; 187: 246–248.
Galangin induces human colon cancer cell death via the mitochondrial dysfunction and caspase-dependent pathway / T.K. Ha, M.E. Kim, J.H. Yoon [et al.] // Exp. Biol. Med. (Maywood). – 2013; 238: 1047–1054.
The Effects of Aqueous Extract of Alpinia Galangal on Gastric Cancer Cells (AGS) and L929 Cells in Vitro / M.-A.-R. Hadjzadeh, H. Ghanbari, Z. Keshavarzi, J. Tavakol-Afshari // Iran. J. Cancer Prev. – 2014; 7: 142–146.
Halliwell, B. A super way to kill cancer cells? / B. Halliwell // Nature Medicine // 2000; 6(10): 1105–1106.
Halliwell, B. Role of free radicals and catalytic metal ions in human disease: an overview / B. Halliwell, J.M. Gutteridge // Methods in Enzymology. – 1990; 186: 1–85.
Han, M. Quercetin suppresses the migration and invasion in human colon cancer Caco-2 cells through regulating toll-like receptor 4/nuclear factor-kappa B pathway / M. Han, Y. Song, X. Zhang // Pharmacogn. Mag. – 2016; 12(Suppl 2): 237–244.
Neurotransmitter metabolic enzymes and antioxidant status on Alzheimer›s disease induced mice treated with Alpinia galanga (L.) / J.C. Hanish Singh, V. Alagarsamy, S. Sathesh Kumar, Y. Narsimha Reddy // Willd. Phytother Res. – 2011; 25: 1061–1067.
Flavonoids protect human retinal pigment epithelial cells from oxidative-stress-induced death / A. Hanneken, F.F. Lin, J. Johnson, P. Maher // Invest Ophthalmol Vis Sci. 2006; 47: 3164–3177.
Harirforoosh, S., Asghar W., Jamali F. Adverse effects of nonsteroidal antiinflammatory drugs: an update of gastrointestinal, cardiovascular and renal complications / S. Harirforoosh, W. Asghar, F. Jamali // J. Pharm Pharm Sci. 2014; 16:821–847.
Hartwell, J.L. Plants Used Against Cancer: A Survey / J.L. Hartwell., Quarterman Publications, Inc., Lawrence, MA, 1982. (reprinted from 11 different issues of Lloydia)
Homeoden-Heel. Catalogus, Baden-Baden: Simile-Gent, 1998. – 204 p.
Homoopatihisches Arzneibuch. – 1. Ausgabe 1978. – Gesatausgabe. – Diese Gesamtausgabe nach der Neufassung 1985 enhalt die Teibande. HAB 1 1978, 1. Nachtrag 1981, 2. Nachtrag 1983, 3. Nachtrag 1985, 4. Nachtrag 1985. – Amtliche Ausgabe. – Deutscher Apotheker Verlag Stuttgart Govi – Verlag GmbH, Frankfurt. – 928 s.
Isolates of Alpinia officinarum Hance as COX-2 inhibitors: Evidence from anti-inflammatory, antioxidant and molecular docking studies / V.S. Honmore, A.D. Kandhare, P.P. Kadam [et al.] // Int. Immunopharmacol. – 2016; 33: 8–17.
Protective effects of myricitrin against osteoporosis via reducing reactive oxygen species and bone-resorbing cytokines / Q. Huang, B. Gao, L. Wang [et al.] // Toxicol Appl Pharmacol. – 2014; 280: 550–560.
Ginsenoside-Rb2 displays anti-osteoporosis effects through reducing oxidative damage and bone-resorbing cytokines during osteogenesis / Q. Huang, B. Gao, Q. Jie [et al.] // Bone. 2014; 66: 306–314.
7-(4-Hydroxyphenyl)-1-phenyl-4E-hepten-3-one, a Diarylheptanoid from Alpinia of?cinarum, Protects Neurons against Amyloid-? Induced Toxicity / X. Huang, G. Tang, Y. Liao [et al.] // Biol. Pharm. Bull. – 2016. Vol. 39, No. 12. - Р. 1961–1967.
Antimicrobial effect by extracts of rhizome of Alpinia officinarum Hance may relate to its inhibition of beta-ketoacyl-ACP reductase / H. Huang, D. Wu, W.X. Tian [et al.] // J. Enzyme. Inhib. Med. Chem. – 2008; 23: 362–368.
The natural flavonoid galangin inhibits osteoclastic bone destruction and osteoclastogenesis by suppressing NF-?B in collagen-induced arthritis and bone marrow-derived macrophages / J.E. Huh, I.T. Junq, J. Choi [et al.] // Eur J Pharmacol. 2013; 698: 57–66.
The effects of galangin on a mouse model of vitiligo induced by hydroquinone / S.X. Huo, X.M. Liu, C.H. Ge [et al.] // Phytother. Res. – 2014; 28: 1533–1538.
Essential oil composition and antimicrobial activities of two closely related species, Alpinia mutica Roxb. and Alpinia latilabris Ridl., from Peninsular Malaysia / H. Ibrahim, Y. Sivasothy, D.R. Syamsir [et al.] // Scientific World J. – 2014. – Vol. 2014: 430831.
Indian Council of Medical Research, Medicinal Plants of India, Vol. 1, Indian Council of Medical Research, Cambridge Printing Works, New Delhi, 1976.
Indian Council of Medical Research, Medicinal Plants of India, Vol. 2, Indian Council of Medical Research, Cambridge Printing Works, New Delhi, 1987.
Antitumour principles from Alpinia galangal / H. Itokawa, H. Morita, T. Sumitomo [et al.] // Planta Med. – 1987; 53: 32–33.
In vitro cytotoxicity of norviburtinal and isopinnatal from Kigelia pinnata against cancer cell lines / S.J. Jackson, P.J. Houghton, S. Retsas, A. Photiou // Planta Med. – 2000; 66: 758–761.
Ethacrynic acid analogues lacking the alpha, beta-unsaturated carbonyl unit – potential anti-metastatic drugs / R.F. Janser, R.K. Meka, Z.E. Bryant [et al.] // Bioorg. Med. Chem. Lett. – 2010; 20: 1848–1850.
Hydrogen peroxide-induced apoptosis in pc12 cells and the protective effect of puerarin / B. Jiang, J.H. Liu, Y.M. Bao, L.J. An // Cell Biology International. – 2003; 27(12): 1025–1031.
Anti-inflammatory effects of galangin on lipopolysaccharide-activated macrophages via ERK and NF-kappa B pathway regulation / Y.C. Jung, M.E. Kim, J.H. Yoon [et al.] // Immunopharmacol. Immunotoxicol. – 2014; 36: 426–432.
Diarylheptanoids from Alpinia officinarum Cause Distinct but Overlapping Effects on the Translatome of B Lymphoblastoid Cells / T. Kakegawa, S. Takase, E. Masubuchi, K. Yasukawa // Evidence-Based Complementary and Alternative Medicine. – 2014; Vol. 2014: 204797–204797.
Elastase release by stimulated neutrophils inhibited by flavonoids: importance of the catechol group / A. Kanashiro, J.C. Souza, L.M. Kabeya [et al.] // Zeit F?r Naturforschung. 2007. C.62:357–361.
Osteoblastogenesis and osteoprotection enhanced by flavonolignan silibinin in osteoblasts and osteoclasts / J.L. Kim, S.W. Kang, M.K. Kang [et al.] // J Cell Biochem. 2012;113:247–259.
Localization and expression of inducible nitric oxide synthase in biopsies from patients with interstitial cystitis / L.R. Koskela, T. Thiel, I. Ehr?n [et al.] // J. Urol. – 2008. –Vol. 180. – P.737–741.
LC–MS/MS analysis, antioxidant and anticholinergic properties of galanga (Alpinia officinarum Hance) rhizomes / L.P. Ko?se, I?. Gu?lc?in, A.C. Go?ren [et al.] // Ind. Crops Prod. – 2015; 74: 712–721.
Kumar, S. Chemistry and biological activities of flavonoids: an overview / S. Kumar, A.K. Pandey // Scient. World J. – 2013; Vol. 2013: 162750.
Laine, L. Approaches to nonsteroidal anti-inflammatory drug use in the high-risk patient. Gastroenterology / L. Laine. – 2001; 120: 594–606.
Lanas A, Baron JA, Sandler RS, Horgan K, Bolognese J, Oxenius B, Quan H, Watson D, Cook TJ, Schoen R, et al. Peptic ulcer and bleeding events associated with rofecoxib in a 3-year colorectal adenoma chemoprevention trial. Gastroenterology. 2007. – 132: 490–497.
Effect of sesaminol glucosides on ?-amyloid-induced PC12 cell death through antioxidant mechanisms / S.Y. Lee, T.Y. Ha, D.J. Son [et al.] // Neuroscience Research. – 2005; 52(4): 330–341.
Lee, C.C. Cytotoxicity of plants from Malaysia and Thailand used traditionally to treat cancer / C.C. Lee, P. Houghton // J. Ethnopharmacol. – 2005; 100: 237–243.
Screening of medicinal plant extracts for antioxidant activity / S.E. Lee, H.J. Hwang, J.S. Ha [et al.] // Life Sci. – 2003; 73: 167–179.
Synergistic effects of the combination of galangin with gentamicin against methicillin-resistant Staphylococcus aureus / Y.S. Lee, O.H. Kang, J.G. Choi [et al.] // J. Microbiol. –2008; 46: 283–288.
Anti-inflammatory, anti-nociceptive, and anti-psychiatric effects by the rhizomes of Alpinia officinarum on complete Freund’s adjuvant-induced arthritis in rats / J. Lee, K.A. Kim, S. Jeong [et al.] // J. Ethnopharmacol. – 2009; 126: 258–264.
Effects of hydrogen peroxide (H2O2) on alkaline phosphatase activity and matrix mineralisation of odontoblast and osteoblast cell lines / D.H. Lee, B.S. Lim, Y.K. Lee, H.C. Yang // Cell Biol Toxicol. 2006; 22: 39–46.
Lesser Galangal – Alpinia officinarum // In book: PDR for Herbal Medicines (Physician›s Desk Reference for Herbal Medicines); 4th Edition / by Thomson Healthcare (Author); published by Thomson Reuters, 2007. – 990 р. (Р. 467–468).
Leung, P.C. Herbal treatment for osteoporosis: a current review / P.C. Leung, W.S. Siu // J Tradit Complment Med. 2013;3:82–87.
Li, B.H. Presence of fatty acid synthase inhibitors in the rhizome of Alpinia officinarum Hance / B.H. Li, W. Tian // J. Enzyme Inhib. Med. Chem. - 2003; 18: 349–356.
Lim T.K. Edible Medicinal and Non-Medicinal Plants: Modified Stems, Roots, Bulbs; Vol. 12 / T.K. Lim. – London: Springer, 2002. – Р. 178.
Antihyperlipidemic bioactivity of Alpinia officinarum (Hance) Farw Zingiberaceae can be attributed to the coexistance of curcumin, polyphenolics, dietary fibers and phytosterols / L.Y. Lin, C.C. Peng, X.Y. Yeh [et al.] // Food Funct. – 2015; 6: 1600–1610.
List, P.H. Hager’s Handbuch der Pharmazeutischen Praxis, Vols. 2-6. / P.H. List, L. Hohammer. – Springer- Verlag, Berlin, 1969–1979.
Liu, C.N. Antagonistic storage method of traditional Chinese medicinal material / C.N. Liu // J. Chin. Med. Mater. – 1987; 4: 36. – doi: 10.13863/j.issn1001-4454.1987.04.022.
New cytotoxic diarylheptanoids from the rhizomes of Alpinia officinarum Hance / D. Liu, Y.W. Liu, F.Q. Guan, J.Y. Liang // Fitoterapia. – 2014; 96: 76–80.
A new dimeric diarylheptanoid from the rhizomes of Alpinia officinarum / D. Liu, W. Qu, L. Zhao [et al.] // Chin. J. Nat. Med. – 2014; 12: 139–141.
Dimeric Diarylheptanoids with Neuroprotective Activities from Rhizomes of Alpinia officinarum / H. Liu, X. Wang, Q. Shi [et al.] // ACS Omega. – 2020; 5(17): 10167–10175. Published 2020 Apr 22.
Evaluation of Diarylheptanoid–Terpene Adduct Enantiomers from Alpinia officinarum for Neuroprotective Activities / H. Liu, Zh.-L. Wu, X.- J. Huang [et al.] // J. Natur. Prod. – 2018. – 81(1) .
Discrimination of Two Cultivars of Alpinia Officinarum Hance Using an Electronic Nose and Gas Chromatography-Mass Spectrometry Coupled with Chemometrics / Q. Long, Z. Li, B. Han [et al.] // Sensors (Basel, Switzerland). – 2019 Jan 30; 19(3): 572.
Mechanism and inhibitory effect of galangin and its flavonoid mixture from Alpinia officinarum on mushroom tyrosinase and B16 murine melanoma cells / Lu Y.H., Z.T. Lin-Tao Wang, D.Z. Wei, H.B. Xiang // J. Enzyme Inhib. Med. Chem. – 2007; 22: 433–438.
Protective effect of galangin in Concanavalin A-induced hepatitis in mice / Q. Luo, L. Zhu, J. Ding [et al.] // Drug Des. Dev. Ther. – 2015; 9: 2983–2992.
L?, J. Repellent and Contact Toxicity of Alpinia officinarum Rhizome Extract against Lasioderma serricorne Adults / J. L?, D. Ma // PLoS One. – 2015; 10(8): e0135631. - Published 2015 Aug 20.
Isolation and characterization of some antioxidative compounds from the rhizomes of smaller galangal (Alpinia officinarum Hance) / T.N. Ly, M. Shimoyamada, K. Kato, R. Yamauchi // J. Agricult. Food Chem. – 2003; 51(17): 4924–4929.
Antioxidative compounds isolated from the rhizomes of smaller galangal (Alpinia officinarum Hance) / T.N. Ly, M. Shimoyamada, K. Kato, R. Yamauchi // Biofactors. – 2004; 21(1–4): 305–308.
Isolation and structural elucidation of some glycosides from the rhizomes of smaller Galanga (Alpinia officinarum Hance) / T.N. Ly, R. Yamauchi, M. Shimoyamada, K. Kato, // J. Agricult. Food Chem. - 2002; 50(17): 4919–4924.
Madaus, G., Lehrbuch der Biologischen Hilfmittel, Vol. 1-3 / G. Madaus. – Georg Olms Verlag, Hildescheim, 1976, reprint of 1938 Madaus
Malfertheiner, P. Peptic ulcer disease / P. Malfertheiner, F.K. Chan, K.E. Mccoll // Lancet. 2009. 374:1449–1461.
Manolagas, S.C. From oestrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis / S.C. Manolagas // Endocr Rev. 2010;31:266–300.
Marx, R.E. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic / R.E. Marx // J Oral Maxillofac Surg. 2003;61:1115–1117.
Inhibitors from the rhizomes of Alpinia officinarum on production of nitric oxide in lipopolysaccharide-activated macrophages and the structural requirements of diarylheptanoids for the activity / H. Matsuda, S. Ando, T. Kato T. [et al.] // Bioorg Med. Chem. – 2006; 14: 138–142.
Melanogenesis inhibitors from the rhizomes of Alpinia officinarum in B16 melanoma cells / Matsuda H., Nakashima S., Oda Y., Nakamura S., Yoshikawa M. // Bioorg Med. Chem. – 2009; 17: 6048–6053.
Mazzanti, G. Analgesic anti-inflammatory action of Pfaffia paniculata (martius) kuntze / G. Mazzanti, L. Braghiroli // Phytother. Res. – 1994; 8: 413–416.
American Herbal Products Association’s Botanical Safety Handbook / M. McGuffin [et al.], Eds. – CRC Press, Boca Raton, FL, 1997.
Megahed, N.A. Antivirus-built environment: Lessons learned from Covid-19 pandemic / N.A. Megahed, E.M. Ghoneim // Sustain Cities Soc. – 2020 Oct; 61:102350.
Dissecting the Pharmacophore of Curcumin. Which Structural Element Is Critical for Which Action? / A. Minassi, G. Sa?nchez-Duffhues, J.A. Collado [et al.] // J. Nat. Prod. – 2013; 76: 1105?1112.
Nitric oxide-mediated mechanism of neuronal nitric oxide synthase and inducible nitric oxide synthase expression during hypoxia in the cerebral cortex of newborn piglets / O.P. Mishra, R. Mishra, Q.M. Ashraf, M. Delivoria-Papadopoulos // Neuroscience. – 2006. – Vol. 140. – P.857–863.
Reactive oxygen species in inflammation and tissue injury / M. Mittal, M.R. Siddiqui, K. Tran [et al.] // Antioxid Redox Signal. 2014; 20:1126–67.
Chinese herbal medicine for bone health / E. Mukwaya, F. Xu, M.S. Wong, Y. Zhang // Pharm Biol. 2014; 52:1223–1228.
Munnoli, P.M. Post-COVID-19 precautions based on lessons learned from past pandemics: a review / P.M. Munnoli, S. Nabapure, G. Yeshavanth // Z. Gesundh. Wiss. – 2020 Aug 4: 1-9.
Structure-activity relationships of (1-S’)-1’-acetoxychavicol acetate, a major constituent of a Southeast Asian condiment plant Languas galangal on the inhibition of tumor-promoter-induced Epstein-Barr virus activation / Murakami A., Toyota K., Ohura S. [et al.] // J. Agric. Food. Chem. – 2000; 48: 1518–1523.
Ovariectomy induces oxidative stress and impairs bone antioxidant system in adult rats / S. Muthusami, I. Ramachandran, B. Muthusamy [et al.] // Clin Chim Acta. 2005; 360:81–86. [PubMed] [Google Scholar]
A novel diarylheptanoid-bearing sesquiterpene moiety from the rhizomes of Alpinia officinarum / W. Na, Z.L. Zhou, Q. Wei [et al.] // Nat. Prod. Res. – 2016; 30: 2344–2349.
Extraction and identification of water soluble compounds in palm pressed fiber by SC-CO2and GC-MS / H.L. Nang, C.Y. May, M.A. Ngan, C.C. Hock [et al.] // Am. J. Environ. Sci. – 2007; 3: 54–59.
The anti-inflammatory role of vitamin e in prevention of osteoporosis / A.S. Nazrun, M. Norazlina, M. Norliza, S.I. Nirwana // Adv Pharmacol Sci. 2012; 2012 Article ID 142702, 7 pages.
Nimse, S.B. Free radicals, natural antioxidants and their reaction mechanisms / S.B. Nimse, D. Pal // RSC Adv. – 2015; 5: 27986–8006. [Google Scholar]
Nrf2-Keap1 activation, a promising strategy in the prevention of cancer / O.A. Ojo, B. Ajiboye, A. Fadaka [et al.] // Frees Radic Antioxid. – 2017; 7: 1–7.
Antiproliferative activities of lesser galangal (Alpinia officinarum Hance), turmeric (Curcuma longa L.). and ginger (Zingiber officinale Rosc.) against acute monocytic leukemia / S.N. Omoregie, F.O. Omoruyi, V.F. Wright [et al.] // J. Med. Food. – 2013; 16: 647–55.
A guide to transient expression of membrane proteins in HEK-293 cells for functional characterization / A. Ooi, A. Wong, L. Esau [et al.] // Front Physiol. – 2016; 7: 300.
Role of flavonoids on oxidative stress and mineral contents in the retinoic acid-induced bone loss model of rat / N. Orsolic, E. Goluza, D. Dikic [et al.] // Eur J Nutr. 2014;53:1217–1227.
Parekh, J. Efficacy of aqueous and methanol extracts of some medicinal plants for potential antibacterial activity / J. Parekh, D. Jadeja, S. Chanda // Turk. J. Biol. – 2005; 29: 203–210.
Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women / L.Y. Park-Wyllie, M.M. Mamdani, D.N. Juurlink [et al.] // JAMA. 2011;305:783–789.
Pharmacopoeia of the People’s Republic of China. Beijing: Chemical Industry Press / Editor: The State Pharmacopoeia Commission of the People’s Republic of China. – Beijing: People‘s Medical Publishing House, 2005.
Pietta, P.G. Flavonoids as antioxidants / P.G. Pietta // J. Nat. Prod. – 2000; 63: 1035–42.
Therapeutic Potential of Alpinia officinarum / M.K. Pillai, D.J. Young, Hj.A. Bin, H.M. Majid // Mini Rev Med Chem. – 2018; 18 (14): 1220–1232.
Polvani, S. PPARgamma and oxidative stress: Con(beta) catenating NRF2 and FOXO / S. Polvani, M. Tarocchi, A. Galli // PPAR Res. 2012;2012 Article ID 641087, 15 pages.
Quoted in Strehlow Wighard, Hertzka Cottfried. Hildegard of Bingen’s Medicine. – Inner Traditions, 1998. – P. 37.
Molecular basis of the anti-inflammatory potential of a diarylheptanoid in murine macrophage RAW 264.7 cells / B.R. Rajaganapathy, K. Thirugnanam, M.V. Shanmuganathan [et al.] // Adv. Biol. Chem. – 2013; 3: 541–548.
Antioxidant and anti-inflammatory activities of selected Chinese medicinal plants and their relation with antioxidant content / A.S. Ravipati, L. Zhang, S.R. Koyyalamudi [et al.] // BMC Complement. Altern. Med. – 2012; 12: 173.
Rawlings, M. The gene encoding Escherichia coli acyl carrier protein lies within a cluster of fatty acid biosynthetic genes / M. Rawlings M., J.E. Jr. Cronan // J. Biol. Chem. – 1992; 267: 5751–5754.
Reid K., Wright V., Omoregie S. Anticancer properties of Alpinia officinarum (lesser galangal) – A mini review // Int. J. Adv. Res. – 2016; 4: 300–306.
Oxidative stress, inflammation, and cancer: how are they linked? / S. Reuter, S.C. Gupta, M.M. Chaturvedi, B.B. Aggarwal // Free Radic Biol Med. 2010;49:1603–16.
Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies / A. Rimessi, M. Previati, F. Nigro [et al.] // Int J Biochem Cell Biol. – 2016; 81(Pt B): 281–293.
Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis / R. Rizzoli, J.Y. Reginster, S. Boonen [et al.] // Calcif Tissue Int. 2011;89:91–104.
Isosorbide 5 mononitrate administration increases nitric oxide blood levels and reduces proteinuria in IgA glomerulonephritis patients with abnormal urinary endothelin cyclic GMP ratio / D. Roccatello, G. Mengozzi, M. Ferro [et al.] // Clin. Nephrol. – 1995. – Vol. 44. – P.163–169.
Novel biomarkers in the diagnosis of chronic kidney disease and the prediction of its outcome / J. Rysz, A.I.D. Gluba-Brz?zka, B. Franczyk [et al.] // Int. J. Mol. Sci. – 2017; 18: 1702.
Sak, K. Cytotoxicity of dietary flavonoids on different human cancer types / K. Sak // Pharmacogn. Rev. – 2014; 8: 122–146.
Quercitrin and taxifolin stimulate osteoblast differentiation in MC3T3-E1 cells and inhibit osteoclastogenesis in RAW 264.7 cells / M. Satue, M. Arriero Mdel, M. Monjo, J.M. Ramis // Biochem Pharmacol. 2013;86:1476–1486.
Shahid Akbar. Handbook of 200 Medicinal Plants: A Comprehensive Review of Their Traditional Medical Uses and Scientific Justifications / Akbar Shahid. – Springer Nature Switzerland AG 2020. – 2020. – Р. 217–224.
Effects of the hook of Uncaria rhynchophylla on neurotoxicity in the 6-hydroxydopamine model of Parkinson’s disease / J.S. Shim, H.G. Kim, M.S. Ju [et al.] // J. Ethnopharmacology. – 2009; 126(2): 361–365.
Galangin dampens mice lipopolysaccharide-induced acute lung injury / Y.S. Shu, W. Tao, Q.B. Miao [et al.] // Inflammation. 2014;37:1661–1668.
Sivakumar, A.S. Effect of galangin supplementation on oxidative damage and inflammatory changes in fructose-fed rat liver / A.S. Sivakumar, C.V. Anuradha // Chem Biol Interact. – 2011. 193:141–148.
Sivakumar, A.S. Dose-dependent effect of galangin on fructose-mediated insulin resistance and oxidative events in rat kidney / A.S. Sivakumar, P. Viswanathan, C.V. Anuradha // Redox Rep. – 2010;15:224–232.
Smith, M.B. Advanced Organic Chemistry: Reactions, Mechanisms and Structure; 6th ed. / M.B. Smith, J. March. – New York: Wiley-Interscience, 2007.
Sostres, C. Nonsteroidal anti-inflammatory drugs and upper and lower gastrointestinal mucosal damage / C. Sostres, C.J. Gargallo, A. Lanas // Arthritis Res Ther. – 2013. 15:S3.
Spencer, J.P. The interactions of flavonoids within neuronal signalling pathways / J.P. Spencer // Genes Nutr. – 2007; 2: 257–273.
Antioxidant and antimicrobial activity of Alpinia officinarum / A.R. Srividya, S.P. Dhanabal, V.K. Misra, G. Suja // Indian J. Pharm. Sci. – 2010; 72: 145–148.
Steinmetz, E.F. Codex Vegetabilis. All Botanical Drugs / E.F. Steinmetz. – Keizersgracht 347, Amsterdam, 1957.
Case-control study of postmenopausal hormone replacement therapy and endometrial cancer / B.L. Strom, R. Schinnar, A.L. Weber [et al.] // Am J Epidemiol. – 2006;164:775–786.
Antiosteoporotic effects of Alpinia officinarum Hance through stimulation of osteoblasts associated with antioxidant effects / Y. Su, Y. Chen, Y. Liu [et al.] // J. Orthop. Translat. – 2015 Oct 29; 4: 75-91.
Protective effect of albiflorin against oxidative-stress-mediated toxicity in osteoblast-like MC3T3-E1 cells / K.S. Suh, E.M. Choi, Y.S. Lee, Y.S. Kim // Fitoterapia. – 2013;89:33–41.
Suja, S. Inhibition of in vitro cytotoxic effect evoked by Alpinia galanga and Alpinia officinarum on PC – 3 cell line / S. Suja, P. Chinnaswamy // Anc. Sci. Life. – 2008; 27: 33–40.
Sultana, B. Effect of extraction solvent / technique on the antioxidant activity of selected medicinal plant extracts / B. Sultana, F. Anwar, M. Ashraf // Molecules. – 2009; 14: 2167–2180.
New cytotoxic diarylheptanoids from the rhizomes of Alpinia officinarum / Y. Sun, K. Tabata, H. Matsubara [et al.] // Planta Medica. – 2008; 74(4): 427–431.
Diarylheptanoids derived from Alpinia officinarum induce apoptosis, S-phase arrest and differentiation in human neuroblastoma cells / K. Tabata, Y. Yamazaki, M. Okada [et al.] // Anticancer Res. – 2009; 29: 4981–4988.
Identification of chemical constituents occurring in leaves of Alpinia officinarum / Y.F. Tan, H.L. Li, Y.B. Li [et al.] // Chin. J. Exp. Tradit. Med. Formula. – 2015; 3: 37–40.
A natural diarylheptanoid promotes neuronal differentiation via activating ERK and PI3K-Akt dependent pathways / G. Tang, X. Dong, X. Huang [et al.] // Neuroscience. – 2015. – Vol. 303. – P. 389-401.
Tschirch A. Handbuch der Pharmakognosie [A handbook of pharmacognosy]. - Leipzig: Verlag CH Tauchnitz, 1923.
Turner, J. Spice: The history of a Temptation / J. Turner. – US: Vintage (2005). – P.195; Knopf Doubleday Publishing Group, 2008. – 384 р.
Evaluation of cytotoxic and mutagenic effects of coriolus versicolor and Funalia trogii extracts on mammalian cells / A. ?nyayar, M. Demirbilek, M. Turkoglu [et al.] // Drug. Chem. Toxicol. – 2006; 29(1): 69–83.
Urquiza-Martinez, M.V. Antioxidant capacity of food / M.V. Urquiza-Martinez, B.F. Navarro // Free Radic Antioxid. – 2016; 6: 1–12.
Chemical composition of the fractions of leaf oil of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm. and antimicrobial activity / C.P. Vict?rio, D.S. Alviano, C.S. Alviano, C.L.S. Lage // Brazilian. J. Pharmacognosy. – 2009; 19(3): 697–701.
Research on Аlpinia officinarum Hance oil against experimental gastrelcosis and action mechanism / H.-Y. Wang, Ya-M. Liu, H.-Y. Li [et al.].
Watt, G. Dictionary of the Economic Products of India, 6 vols. / G. Watt. – Nav Bharat Offset Process, Delhi, India, 1889–1892, reprint 1972.
Effect of different extraction parts of galangal on experimental gastric ulcer / N. Wei, Y.F. Tan, F. Chen // J. Hainan Med Univ. 2015. – 21:158–160. http://scholar.google.com/scholar_lookup?hl=en&volume=21&publication_year=2015&pages=158-160&author=N+Wei&author=YF+Tan&author=F+Chen&author=H+Li&author=JQ.+Zhang&title=Effect+of+different+extraction+parts+of+galangal+on+experimental+gastric+ulcer
Anovel diarylheptanoid-bearing sesquiterpene moiety from the rhizomes of Alpinia officinarum / N. Wei, Z. Zhou, Q. Wei [et al.] // Nat. Prod. Res. –2016; 30: 2344–2349.
Wen, Y.Y. A new diterpenoid from Alpinia Zerumbet / Y.Y. Wen, Y.F. Chen, X.M. Xie // Acta Botanica Sinica. – 1997; 399(10): 983–984.
Two anti-inflammatory diterpenes from the rhizomes of Alpinia officinarum Hance / T. Wen, X.K. Wang, C. Liu, H. Liu // J. Pharm. Biomed. Sci. – 2016; 6: 479–482.
Wickens, A.P. Ageing and the free radical theory / A.P. Wickens // Respiration Physiology. – 2001; 128(3): 379–391.
Wijayaratne, L.K.W. Methoprene and control of stored-product insects / L.K.W. Wijayaratne, F.H. Arthur, S. Whyard // J. Stored. Prod. Res. 2016. – Vol. 76.
Williamson, E.M. Potter›s New Cyclopaedia of Botanical Drugs and Preparations, revised ed. / E.M. Williamson and F.J. Evans. – Saffron Walden, the C.W. Daniel Co., Ltd., Essex, UK, 1988, reprint 1989.
Wolfe, M.M. Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs / M.M. Wolfe, D.R. Lichtenstein, G. Singh // New Engl. J. Med. – 1999; 340: 1888–1899.
7-(4-Hydroxy-3-methoxyphenyl)-1-phenyl-4E-hepten-3-one alleviates A?1-42 induced cytotoxicity through PI3K-mTOR pathways / H.L. Xiao, Q.H. Zhang, Y.H. Peng [et al.] // Biochemical and biophysical research communications. – 2017. – Vol. 484. – № 2. – Р.365–371.
Antibacterial activities of flavonoids: structure-activity relationship and mechanism / Xie Y., W. Yang, F. Tang [et al.] // Curr. Med. Chem. – 2015; 22: 132–149.
Chemical Constituents of Supercritical Extracts from Alpinia officinarum and the Feeding Deterrent Activity against Tribolium castaneum / M. Xin, S. Guo, W. Zhang [et al.] // Molecules (Basel, Switzerland). – 2017. – 22(4): 647.
Epimedium-derived flavonoids modulate the balance between osteogenic differentiation and adipogenic differentiation in bone marrow stromal cells of ovariectomised rats via Wnt/?-catenin signal pathway activation / Y.X. Xu, C.L. Wu, Y. Wu [et al.] // Chin J Integr Med. 2012;18:909–917.
Yadav, P.N. diarylheptanoid from lesser galangal (Alpinia officinarum) inhibits pro-inflammatory mediators viainhibition of mitogen-activated protein kinase, p44/42, and transcription factor nuclear factor-kappa B / P.N. Yadav, Z. Liu, M.M. Rafi // J. Pharmacol. Exp. Ther. – 2003; 305: 925–931.
Organic acids and water-soluble phenolics produced by Paxillus sp 60/92 together show antifungal activity against Pythium vexans under acidic culture conditions / K. Yamaji, H. Ishimoto, N. Usui, S. Mori // Mycorrhiza. – 2005; 15: 17–23.
Tanshinol attenuates the deleterious effects of oxidative stress on osteoblastic differentiation via Wnt/FoxO3a signaling / Y.J. Yang, Y.J. Su, D. Wang [et al.] // Oxid Med Cell Longev. 2013;2013 Article ID 351895, 18 pages.
Yang, R.Z. Plants used for pest control in China: a literature review / R.Z. Yang, C.S. Tang // Econ. Bot. – 1988; 42: 376–406.
Motohashi S. Inhibitory effect of the rhizomes of Alpinia officinarum on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin / K. Yasukawa, Y. Sun, S. Kitanaka [et al.] // J. Nat. Med. – 2008; 62: 374–378.
Analysis of active constituents of Alpinia officinarum Hance from different localities of Hainan province / H.L. Zhai, Q. Li, H. Wang [et al.] // J. Trop. Biol. – 2014; 2: 188–193.
Three new antibacterial active diarylheptanoids from Alpinia officinarum / B.B. Zhang, Y. Dai, Z.X. Liao, L.S. Ding // Fitoterapia. – 2010; 81: 948–952. – doi: 10.1016/j.fitote.2010.06.015
Galangin induces B16F10 melanoma cell apoptosis via mitochondrial pathway and sustained activation of p38 MAPK / W. Zhang, Y. Lan, Q. Huang, Z. Hua // Cytotechnology. – 2013; 65: 447–455.
Zhang, W.-J. The Genus Alpinia: A Review of Its Phytochemistry and Pharmacology / W.-J. Zhang, J.-G. Luo, L.-Y. Kong // World J Tradit Chin Med 2016; 2(1): 26–41.
Simultaneous quantification of seventeen bioactive components in rhizome and aerial parts of Alpinia officinarum Hance using LC-MS/MS / J.Q. Zhang, Y. Wang, H.L. Li [et al.] // Anal. Methods. – 2015; 7: 4919.
Galangin induces apoptosis in hepatocellular carcinoma cells through the caspase 8/t-Bid mitochondrial pathway / H.T. Zhang, J. Wu, M. Wen [et al.] // J. Asian Nat. Prod. Res. – 2012; 14: 626–33.
Flavonoids from the Aerial Parts of Alpinia officinarum / H. Zhang, L.X. Xu, P. Wu, X.Y. Wei // J. Trop. Subtrop. Bot. – 2014; 22: 89–92.
Zhu, J.X. Progress on Alpinia officinarum Hance / J.X. Zhu, W. He, J.C. Ma // Food Drug. – 2009; 11: 68–70.
Galangin inhibits growth of human head and neck squamous carcinoma cells in vitro and in vivo / L. Zhu, Q. Luo, J. Bi [et al.] // Chem. Biol. Interact. – 2014; 224: 149–156.
A new labdane diterpene from the rhizomes of Alpinia officinarum / Q.Y. Zou, H.F. Wu, Y.L. Tang, D.Z. Chen // Nat. Prod. Res. – 2016; 30: 1–6.
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